Research Progress on Epinephrine - 9781604564433
  • Research Progress on Epinephrine - 9781604564433

Research Progress on Epinephrine - 9781604564433

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€270.01
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Description
This book is devoted to new research on epinephrine (INN) sometimes spelled epinephrin or adrenalin respectively, which is a hormone when carried in the blood and a neurotransmitter when it is released across a neuronal synapse. It is a catecholamine, a sympathomimetic monoamine derived from the amino acids phenylalanine and tyrosine. When secreted into the bloodstream, it rapidly prepares the body for action in emergency situations. The hormone boosts the supply of oxygen and glucose to the brain and muscles, while suppressing other non-emergency bodily processes (digestion in particular). It increases heart rate and stroke volume, dilates the pupils, and constricts arterioles in the skin and gut while dilating arterioles in skeletal muscles. It elevates the blood sugar level by increasing catalysis of glycogen to glucose in the liver, and at the same time begins the breakdown of lipids in fat cells. Like some other stress hormones, epinephrine has a suppressive effect on the immune system. Although epinephrine does not have any psychoactive effects, stress or arousal also releases norepinephrine in the brain. Norepinephrine has similar actions in the body, but is also psychoactive. Epinephrine is used as a drug to treat cardiac arrest and other cardiac dysrhythmias resulting in diminished or absent cardiac output, its action is to increase peripheral resistance via a1-adrenoceptor vasoconstriction, so that blood is shunted to the body's core, and the a1-adrenoceptor response which is increased cardiac rate and output (the speed and pronouncement of heart beats). This beneficial action comes with a significant negative consequence -- increased cardiac irritability -- which may lead to additional complications immediately following an otherwise successful resuscitation. Alternatives to this treatment include vasopressin, a powerful antidiuretic which also increases peripheral vascular resistance leading to blood shunting via vasoconstriction, but without the attendant increase in myocardial irritability.
Product Details
10 Items

Data sheet

Type
Textbook
Author
Roger I Gorman, Arnold G Lawson
Format
Hardcover
Language
English
Item Height
180mm
Item Width
260mm
Number of Pages
161 Pages
Item Weight
536g
Publisher
NOVA Science Publishers
Publication Year
2008

Specific References

ISBN
9781604564433
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