Statistical Mechanics, Protein Structure, and Protein Substra... - 9781489913517
  • Statistical Mechanics, Protein Structure, and Protein Substra... - 9781489913517

Statistical Mechanics, Protein Structure, and Protein Substra... - 9781489913517

New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ... Read moreabout the conditionNew: A new, unread, unused book in perfect condition with no missing or damaged pages. See the seller's listing for full details. See all condition definitionsopens in a new window or tab
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Description
A number of factors have come together in the last couple of decades to define the emerging interdisciplinary field of structural molecular biology. First, there has been the considerable growth in our ability to obtain atomic-resolution structural data for biological molecules in general, and proteins in particular. This is a result of advances in technique, both in x-ray crystallography, driven by the development of electronic detectors and of synchrotron radiation x-ray sources, and by the development ofNMR techniques which allow for inference of a three-dimensional structure of a protein in solution. Second, there has been the enormous development of techniques in DNA engineering which makes it possible to isolate and clone specific molecules of interest in sufficient quantities to enable structural measurements. In addition, the ability to mutate a given amino acid sequence at will has led to a new branch of biochemistry in which quantitative measurements can be made assessing the influence of a given amino acid on the function of a biological molecule. A third factor, resulting from the exponential increase in computing power available to researchers, has been the emergence of a growing body of people who can take the structural data and use it to build atomic-scale models of biomolecules in order to try and simulate their motions in an aqueous environment, thus helping to provide answers to one of the most basic questions of molecular biology: the relation of structure to function.
Product Details
10 Items

Data sheet

Type
Textbook
Author
Sebastian Doniach
Format
Paperback
Language
English
Item Height
235mm
Item Width
155mm
Number of Pages
406 Pages
Item Weight
640g
Publisher
Springer-Verlag NY Inc.
Publication Year
2013

Specific References

ISBN
9781489913517
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