Mitochondria in Health and in Sickness - 9789811383663
  • Mitochondria in Health and in Sickness - 9789811383663

Mitochondria in Health and in Sickness - 9789811383663

New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ... Read moreabout the conditionNew: A new, unread, unused book in perfect condition with no missing or damaged pages. See the seller's listing for full details. See all condition definitionsopens in a new window or tab
€270.01
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10 Items

Description
Besides bringing together researchers and clinicians from various disciplines to share their scope of research on the seminal role of mitochondria in human disease, this original volume of the book has a broader appeal by exploring the health and disease of mitochondria, with specific emphasis on how mitochondrial dysfunction contributes to the development of various neurodegeneration, cancer, and metabolic disorders. The book also provides a foundational overview of the mitochondrial pathogenic or genetic variants and highlights various analytical tools used in the field of mitochondrial genetics, mitochondrial replacement therapy and strategies geared towards shifting heteroplasmy in individuals with mitochondrial disease, how state-of-the-art omics technologies (proteomics, functional genomics) have been employed to study mitochondrial biology in healthy and disease states, post-translational modifications in the regulation of mitochondrial proteins, and the role of mitochondria in host-pathogen interactions. Current approaches taken to study steady-state characteristics of mitochondrial structure and function in live mammalian cells in the contexts of normal and diseased states, and most recent research efforts to develop compounds with anti-cancer potential by targeting mitochondrial proteases or advances in therapeutic approaches towards mitochondrial disease were also explored. By covering this broad range of topics, our hope is to disseminate a wealth of knowledge on the critical role of mitochondria, and how to probe its function in health and in sickness.
Product Details
10 Items

Data sheet

Type
Textbook
Author
Mohan Babu, Andrea Urbani
Format
Hardcover
Language
English
Item Height
254mm
Item Width
178mm
Number of Pages
277 Pages
Item Weight
967g
Publisher
Springer Verlag, Singapore
Publication Year
2019

Specific References

ISBN
9789811383663
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