Enzyme Inhibition in Drug Discovery and Development - 9780470281741
  • Enzyme Inhibition in Drug Discovery and Development - 9780470281741

Enzyme Inhibition in Drug Discovery and Development - 9780470281741

New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ... Read moreabout the conditionNew: A new, unread, unused book in perfect condition with no missing or damaged pages. See the seller's listing for full details. See all condition definitionsopens in a new window or tab
€283.08
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Description
The science and applied approaches of enzyme inhibition in drug discovery and development Offering a unique approach that includes both the pharmacologic and pharmaco-kinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug discovery and drug development. With chapters written by over fifty leading experts in their fields, Enzyme Inhibition in Drug Discovery and Development fosters a cross-fertilization of pharmacology, drug metabolism, pharmacokinetics, and toxicology by understanding the good inhibitions?desirable pharmacological effects?and bad inhibitions?drug?drug interactions and toxicity. The book discusses: The drug discovery process, including drug discovery strategy, medicinal chemistry, analytical chemistry, drug metabolism, pharmacokinetics, and safety biomarker assessment The manipulations of drug metabolizing enzymes and transporters as well as the negative consequences, such as drug?drug interactions The inhibition of several major drug target pathways, such as the GPCR pathway, the NFkB pathway, and the ion channel pathway Through this focused, single-source reference on the fundamentals of drug discovery and development, researchers in drug metabolism and pharmacokinetics (DMPK) will learn and appreciate target biology in drug discovery, discovery biologists and medicinal chemists will also broaden their understanding of DMPK.
Product Details
10 Items

Data sheet

Type
Textbook
Author
Chuang Lu, Albert P. Li
Format
Hardcover
Language
English
Item Height
244mm
Item Width
167mm
Number of Pages
868 Pages
Item Weight
1324g
Publisher
John Wiley & Sons INC International Concepts
Publication Year
2010

Specific References

ISBN
9780470281741
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