Handbook of Ion Channels - 9781466551404
  • Handbook of Ion Channels - 9781466551404

Handbook of Ion Channels - 9781466551404

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The New Benchmark for Understanding the Latest Developments of Ion Channels Ion channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of cells. In nonexcitable tissues, they also help regulate basic salt balance critical for homeostasis. All of these features make ion channels important targets for pharmaceuticals. Handbook of Ion Channels illustrates the fundamental importance of these membrane proteins to human health and disease. Renowned researchers from around the world introduce the technical aspects of ion channel research, provide a modern guide to the properties of major ion channels, and present powerful methods for modeling ion channel diseases and performing clinical trials for ion channel drugs. Conveniently divided into five parts, the handbook first describes the basic concepts of permeation and gating mechanisms, balancing classic theories and the latest developments. The second part covers the principles and practical issues of both traditional and new ion channel techniques and their applications to channel research. The third part organizes the material to follow the superfamilies of ion channels. This part focuses on the classification, properties, gating mechanisms, function, and pharmacology of established and novel channel types. The fourth part addresses ion channel regulation as well as trafficking and distribution. The final part examines several ion channel-related diseases, discussing genetics, mechanisms, and pharmaceutical advances.
Product Details
10 Items

Data sheet

Type
Textbook
Author
Jie Zheng, Matthew C. Trudeau
Format
Hardcover
Language
English
Item Height
280mm
Item Width
210mm
Number of Pages
691 Pages
Item Weight
2404g
Publisher
Taylor & Francis INC International Concepts
Publication Year
2015

Specific References

ISBN
9781466551404
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