MACPF/CDC Proteins - Agents of Defence, Attack and Invasion - 9789401788809
  • MACPF/CDC Proteins - Agents of Defence, Attack and Invasion - 9789401788809

MACPF/CDC Proteins - Agents of Defence, Attack and Invasion - 9789401788809

New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ... Read moreabout the conditionNew: A new, unread, unused book in perfect condition with no missing or damaged pages. See the seller's listing for full details. See all condition definitionsopens in a new window or tab
€178.06
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Description
This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein super family that was originally discovered because of unexpected structural similarity between a domain present in bacterial cholesterol-dependent cytolysins (CDC) and proteins of the membrane attack complex/perforin (MACPF) family. Members of the MACPF/CDC super family are crucial for many biological processes, being efficient agents of development, defence, attack and invasion of cells and tissues. However, their best-known role is in bacterial pathogenesis and the proper functioning of the vertebrate immune system, via formation of transmembrane pores in target cell membranes. The book contains chapters on the distribution of MACPF/CDC proteins and on aspects of their evolution and structural properties, the similarities between different super family members and functional properties of some of the best known examples. The book also contains an overview of biophysical approaches that may be used in the future to provide further insights into how these interesting proteins function.
Product Details
10 Items

Data sheet

Type
Study Guide
Author
Gregor Anderluh, Robert Gilbert
Format
Hardcover
Language
English
Item Height
235mm
Item Width
155mm
Number of Pages
329 Pages
Item Weight
6387g
Publisher
Springer
Publication Year
2014

Specific References

ISBN
9789401788809
EAN13
9789401788809
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